ARTEMETHER

Product Description

The Niksan Pharmaceutical is among world™s top most manufacturer,supplier, exporter and trader of the Artemether finished formulationsmoreover Artemether API. Niksan Pharmaceutical is the huge manufacturer,exporter and supplier of Artemether. API and formulation situated inAnkleshwar, Gujarat, India.

Niksan Pharmaceutical provides API and finished formulations of Artemether in all overIndian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, UttarPradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam,Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan Pharmaceutical is also large exporter of the API and finishedpharmaceutical products of Artemether in many countries for years. Thecountries where we exporting are Cameroon, Niger, Mali, Somalia, Ghana, Malawi,C´te d™Ivoire, Burkina Faso, Nigeria, Tanzania, Angola, Sudan, Congo “Kinshasa, Uganda, Kenya, Zambia, Pakistan, Yemen, South Africa, Bolivia, SaudiArabia, Colombia, Philippines, Australia, Netherlands, United Kingdom, France,Germany, United States, Canada, Brazil and many more countries.

Artemether belongsto the antimalarial class of medicine. Artemether used in the treatment ofmalaria caused by the plasmodium parasites. Artemether prevents the malaria bykilling the parasite that causes the disease. Artemether give intra muscularinjection.

SYNONYMS: Artemetero, Artemether,Artemetherum, Artemisininelactol methyl ether, Dihydroartemisinin methyl ether,Dihydroqinghaosu methyl ether, methyl-dihydroartemisinine

IUPAC NAME:(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclohexadecane

CASNO: 71963-77-4

FORMULA: C16H26O5

MOLECULAR MASS: 298.37 g/mol

STORAGE CONDITION: Store in cool and dry place,away from direct heat and sun light.

Do not placein bathroom or kitchen.Keep away from children and pets.

HOW TO USE: Take this medication with orwithout food as prescribed by your doctor.

Take thismedication twice a day for 3 days.Take medication with food or milk to preventthe stomach upset.Take Artemether injection intra muscularly.Take themedication regularly to get more benefits.

HOW ARTEMETHER WORKS: Artemetheris peroxide containing anti-malarial medicine. Artemether cause degradation ofhaemoglobin by product and inhibits the O2 carrying capacity in theparasite.Thus Artemether act as anti-malarial medicine by killing andpreventing the growth of plasmodium parasite.

PHARMACOKINETICS: Artemether absorbed in bodyafter the oral and I.M. administration. The absorption of Artemether increaseswhen taken with food. Almost 47%-76% of Artemether binds with the blood plasmaprotein.The half-lie of the medicine is between 1.9-2.2 hours.The Artemethereliminated through the hepatic pathway.

SIDE EFFECTS: The normal side effects likeheadache, sweating, nausea, vomiting, insomnia, stomach pain, cough, fever,chills, and dizziness.Contact your doctor if you see side effects like chestpain, dizziness, and fainting, irregular heartbeats.There are some rareallergic reactions like rash, swelling, itching.

PRECAUTIONS: Tell your doctor if you have anyallergic reactions to Artemether.

Tell yourdoctor if you have any conditions like heart problem, stomach problem, liverproblem, abdominal problem, kidney problem. Artemether causes heart relatedproblem so kindly tell your doctor before using the Artemether medication.

CDSCO APPROVAL: Artemether + Lumefantrineapproved by CDSCO in India in 26.12.2002,

Artemether40mg/80mg + Lumefantrine 240mg/480mg tablets (additional Strength) approved byCDSCO in India in24.06.2008,

 Artemether + Lumefantrine Dispersible tablet(40/80mg + 240/480mg) (Additional Strength) approved by CDSCO in India in 05.08.2008,

 Artemether + Lumefantrine (80mg + 480mg/5ml)Dry syrup approved by CDSCO in India in 30.09.2008,

 Artemether injection approved by CDSCO inIndia in 02.08.1996        

FORMULATIONS AVAILABLE IN MARKET:

Artemether 40 MG tablets

Artemether 80 MG /1ML solution

Artemether 150 MG tablets

Artemether 80 MG+Lumefantrine 480 MG tablets

Artemether 20 MG+Lumefantrine 120 MG /ML solution

Artemether 20 MG+Lumefantrine 120 MG tablets

Artemether 40 MG+Lumefantrine 240 MG tablets

Artemether 80 MG+Lumefantrine 840 MG tablets

Artemether 60 MG+Lumefantrine 360 MG tablets

Artemether 40 MG+Lumefantrine 240 MG /5 ML solutions

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult