CLOBETASOL PROPIONATE

Product Description

Niksan Pharmaceutical is one of the leading Manufacturer, Exporter, Distributor, and Supplier of Clobetasol Propionate in Ankleshwar, Gujarat, India. To understand the largest accomplishment of clients, we present these products at very realistic price ranges. Niksan Pharmaceutical and Niksan group companies are now adays one of the largest manufacturer and exporter of Clobetasol Propionate API and also finished formulations.

Niksan Pharmaceutical provides Clobetasol Propionateto all states of India like Punjab,Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi, TamilNadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and Madhya Pradesh etc We also give gift samples to the companies for R&D purpose.

Niksan Pharmaceutical is one of leading manufacturer and exporter ofClobetasol Propionatefor many years in all the countries like Puerto Rico, United States, Nepal, Philippines, HongKong, Nigeria, Bangladesh, United Arab Emirates, Pakistan, Taiwan, Singapore, Malaysia,Canada, Indonesia, Thailand, New Zealand, Vietnam, Israel, United Kingdome, SaudiArabia, Chile, Australia, Colombia, France, Germany, Brazil and many other countries.

Clobetasol Propionate is class I corticosteroid medication. Clobetasol Propionate used in the treatment of many skin disease like skin rash, eczema, seborrheic dermatitis, psoriasis, contact dermatitis. Clobetasol Propionate is used in skin infections. Comes in many dosage forms like shampoo,cream, lotions, and ointment

SYNONYMS: Clobetasol 17-propanoate,Clobetasol 17-propionate, Clobetasol propionate, Clobetasol propionate E

IUPAC NAME:(1R,2S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracycloheptadeca-3,6-dien-14-ylpropionate

CAS NO: 25122-46-7FORMULA: C₂₅H₃₂ClFO₅

MOLECULAR MASS: 466.97g/mol

STORAGE CONDITIONS: Store in cool and dry place, away from light and direct heat. Do not place medicine in bathroom or humid place. Keep away from children and pets.

HOW TO USE: Do not use Clobetasol Propionate on face, under arms or on open wounds. Wash and clean the affected area and after that apply a thin film of Clobetasol Propionate gel on the area and gently rub it. Two time a day.

HOW CLOBETASOL PROPIONATE WORKS: Clobetasol Propionate binds with the glucocorticoid receptor and inhibits the pro-inflammatory receptor. Clobetasol Propionate promotes the anti-inflammatory signals to the brain and gives inflammatory effects

PHARMACOKINETICS: Clobetasol Propionate absorbed systemic circulation after the application. Clobetasol Propionate takes 5 hours to reach the peak plasma concentration after using 2 times daily. The bioavailability of Clobetasol Propionate is only 2.09%. The half-life of Clobetasol Propionate is 96hours. The medicine metabolise in liver and after it will excrete by biliary rout.

SIDE EFFECTS: Normally burning, skin irritation, stinging,dry skin, redness my seen at the site where medicine was applied. Contact your doctor If you see some side effects like stretch marks; skin tightening, acne,skin thinning, and unwanted hair grow. Some rare side effects like weakness,fainting, skin burning, rash, itching, weight loss, headache seen in patients.

PRECAUTIONS: Tell your doctor if you are allergic to the medication.If you have medical history like weak immune system, skin problem, poor blood circulation problem, liver problem tell your doctor before using the medication.The medication can temporarily slow down the childs growth so take advice from doctor before giving to children.Do no tuse this medication if you are in pregnancy or in lactation period.

CDSCO APPROVAL: Clobetasol propionate + Ammonium lactategel is approved by CDSCO in India in 07.08.1996

Clobetasol propionatecream/ointment approved by CDSCO in India in October-1987

Clobetasol propionate bulk approved by CDSCO in India in October-1987

Nadifloxacin (1%) + Clobetasol (0.05%) approved by CDSCO in India in 06.10.2003

FORMULATIONS AVAILABLE IN MARKET:

Clobetasol propionate 0.05% w/w cream

Clobetasol propionate 0.05% w/v solution

Clobetasol propionate 0.025% w/w gel

Clobetasol propionate 0.05%w/w + Clotrimazole 1%w/w cream

Clobetasol propionate 0.05% w/w + Miconazole 2%w/w cream

Clobetasol propionate0.05% w/w + Luliconazole 1% w/w cream

Clobetasol propionate0.05% w/w + Terbinafine 1% w/w cream

Clobetasol propionate0.05% w/w + Nadifloxacin 1% w//w cream

Clobetasol propionate0.05% w/w + Salicylic acid 3% w/w cream

Clobetasol propionate0.05% w/w+ Fusidic acid 2% w/w cream

Clobetasol propionate 0.05% w/v+ Salicylic acid 3%w/v gel

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult